2-PIPERIDINEACETAMIDE APHENYL
alpha-Phenylpiperidine-2-acetamide
CAS: 19395-39-2
Molecular Formula: C13H18N2O
2-PIPERIDINEACETAMIDE APHENYL - Names and Identifiers
| Name | alpha-Phenylpiperidine-2-acetamide |
| Synonyms | Einecs 243-019-1 Methylphenidate intermediate 2-PIPERIDINEACETAMIDE APHENYL α-Phenyl-2-piperidineacetamide a-Phenyl-2-piperidineacetamide 2-phenyl-2-(2-piperidine)acetamide alpha-Phenylpiperidine-2-acetamide 2-Phenyl-2-piperidin-2-ylacetamide 2-Phenyl-2-(2-piperidyl)acetamide Hydrate |
| CAS | 19395-39-2 |
| EINECS | 243-019-1 |
| InChI | InChI=1/C13H18N2O/c14-13(16)12(10-6-2-1-3-7-10)11-8-4-5-9-15-11/h1-3,6-7,11-12,15H,4-5,8-9H2,(H2,14,16) |
2-PIPERIDINEACETAMIDE APHENYL - Physico-chemical Properties
| Molecular Formula | C13H18N2O |
| Molar Mass | 218.29 |
| Density | 1.097±0.06 g/cm3(Predicted) |
| Melting Point | 173 °C |
| Boling Point | 406.6±28.0 °C(Predicted) |
| Flash Point | 199.7°C |
| Vapor Presure | 8.01E-07mmHg at 25°C |
| pKa | 16.16±0.50(Predicted) |
| Refractive Index | 1.554 |
2-PIPERIDINEACETAMIDE APHENYL - Introduction
alpha-Phenylpiperidine-2-acetamide (English name: 2-Acetamido-4-phenylpyridine, abbreviated as APP) is an organic compound. Its chemical formula is C14H12N2O and its relative molecular mass is 224.26g/mol.
alpha-Phenylpiperidine-2-acetamide is a white crystalline solid, soluble in some organic solvents such as methanol and ethanol, slightly soluble in chloroform and benzene. It has good thermal and chemical stability.
The compound is mainly used as an intermediate in organic synthesis reactions, and sometimes as one of the raw materials for drug synthesis. It can participate in amination reaction, Nitro reaction, dehydration reaction, etc.
The production method of alpha-Phenylpiperidine-2-acetamide is usually obtained by reacting p-phenylpiperidine-2-acetic acid with acetyl chloride in the presence of a base. The specific step is to react phenylpiperidine-2-acetic acid with acetic anhydride, and then obtain phenylpiperidine-2-acetamide under reduction conditions.
Regarding safety information, alpha-Phenylpiperidine-2-acetamide is an organic compound and care should be taken to avoid prolonged contact with the skin and inhalation of its vapors. During use, it is recommended to wear protective gloves and glasses to ensure operation in a well-ventilated environment. During storage and handling, the relevant safety practices shall be observed. In case of emergency, such as inhalation or skin contact, rinse immediately with water and seek medical help.
alpha-Phenylpiperidine-2-acetamide is a white crystalline solid, soluble in some organic solvents such as methanol and ethanol, slightly soluble in chloroform and benzene. It has good thermal and chemical stability.
The compound is mainly used as an intermediate in organic synthesis reactions, and sometimes as one of the raw materials for drug synthesis. It can participate in amination reaction, Nitro reaction, dehydration reaction, etc.
The production method of alpha-Phenylpiperidine-2-acetamide is usually obtained by reacting p-phenylpiperidine-2-acetic acid with acetyl chloride in the presence of a base. The specific step is to react phenylpiperidine-2-acetic acid with acetic anhydride, and then obtain phenylpiperidine-2-acetamide under reduction conditions.
Regarding safety information, alpha-Phenylpiperidine-2-acetamide is an organic compound and care should be taken to avoid prolonged contact with the skin and inhalation of its vapors. During use, it is recommended to wear protective gloves and glasses to ensure operation in a well-ventilated environment. During storage and handling, the relevant safety practices shall be observed. In case of emergency, such as inhalation or skin contact, rinse immediately with water and seek medical help.
Last Update：2024-04-09 20:02:46
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Mobile: 18916960931
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Product Name: Alpha-Phenylpiperidine-2-Acetamide Visit Supplier Webpage Request for quotationCAS: 19395-39-2
Tel: +86-18821248368
Email: Int06@meryer.com
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